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Wednesday, September 21, 2011

Peptic Ulcer Disease (Gastric & Duodenal Ulcer)

PUD:
The term peptic ulcer disease refers to  ulceration in any part in the gastro-intestinal tract due to imbalance of acid pepsin digestion of the gastro-intestinal tract.
Male are more sufferer than female.



Causes of PUD:
1. Middle aged between 25-30 years
2. Helicobacter pylori infection
3.Drugs- NSAIDs( aspirin, diclofenac etc.)
5. Smoking
6.Alcohol
7. Irregular meal, inadequate mastication

Clical feature
1. Burning pain before or after meal
2. Vomiting may be present or absent
3. Pain is periodic
4. Appetite incresasd in duodenal ulcer and lost in gastric ulcer


Treatment

Genaral
1. Avoid smoking
2. Avoid alcohol
3. Regular and timely diet
4. Avoid spicy and fatty food
5.Tea/coffee in moderate amount

Specific treatment
1. H2 antagonist- ranitidine 
2. Proton pump inhibitor- Omeprazole
3. Atibiotic- Amoxycillin, Metronidazole, Clarithromycin